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A2ALL Human Liver Explants for HIF-1 Alpha Analysis/Comparison

A2ALL Human Liver Explants for HIF-1 Alpha Analysis/Comparison

Purpose:

The primary study objective is to compare levels of HIF-1α (Hypoxia Inducing Factor 1-alpha) expression in HCC tumor explants which have received: 1) no pre-explant embolization; 2) pre-explant TACE; 3) pre-explant Y90 radioembolization; 4) pre-explant radiofrequency ablation, or; 5) a combination of pre-explant therapies.

Inclusion Criteria:

  • Adults, any gender ≥ to 18 years of age

  • Previous, or current diagnosis of hepatocellular carcinoma (clinical or biopsy proven)

  • Resection for hepatoma and/or transplant

  • Patients with diagnosis of hepatocellular carcinoma from 8/1/94 thru 12/31/05 with biopsy, explant and/or liver transplantation here at NMH

Sponsor:

Divisional

Principle Investigator:

Laura Kulik, MD 

Cost:

None

IRB Project Number:

1530-004

Contact:

Patrice Al-Saden, RN
312-503-1058

Last UpdateMarch 25, 2011
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