Dr. Nadler joined the department of urology in 1996. During his residency training at Barnes Hospital/Washington University in St. Louis, MO, Dr. Nadler was twice named outstanding resident by the faculty, and was awarded both an American Cancer Society Clinical Oncology Fellowship and an American Foundation of Urologic Disease National Kidney Foundation Fellowship during his research year. After residency, he was appointed to the faculty of the division of urology at Barnes Hospital/Washington University where he concentrated on laparoscopic and minimally invasive treatment for prostate cancer, kidney cancer, and kidney stones. Since coming to Northwestern, he has published over 100 peer-reviewed papers, and has won awards including Outstanding Resident Teacher of the Year and the Vincent J. O'Conner Jr. Award for Excellence in Teaching from the medical students.

Dr. Nadler's specific areas of interest include robotic prostatectomy where he is concentrating his efforts on outcomes of robotic prostatectomy patients specifically pertaining to erectile function and margin rates. He is also pioneering a technique of robotic partial nephrectomy, which avoids clamping the renal hilum to better preserve kidney function during robotic partial nephrectomy for renal cell cancer. Finally, he continues to do work in the minimally invasive surgical management of complex kidney stones and renal pelvis tumors